Classification of
Cervical Cancer Using Ultrasound Images
V Vinisha1, R Jemila Rose2
1PG student, St.Xavier’s Catholic College of
Engineering, Chunkankadai, India.
2Assistant Professor, St.Xavier’s
Catholic College of Engineering, Chunkankadai, India.
vinisha065@gmail.com, jemila@ sxcce.edu.in,
Abstract – cervical cancer is one of the most common
malignant gynaecological tumours which cause a serious threat to women health.
Different medical imaging techniques are using to detect various cancers. Here
proposed the ultrasound images of uterus is pre-processed and to detect the
cancer. In this method cancer can be successfully identified and thereby help
the doctors for analysing the size and exact location of cancer. The present’s
development of ultrasound system is used for early detection of uterine cancer.
The proposed ultrasound system support different
texture feature standardization, detection and classification. In
classification, the uterine cancer is divided into three stages. 1) Normal 2)
Pre-cancer 3) Cancer after accounting for multiple comparisons, texture
features extracted from abnormal ROIs Compared to texture features extracted
from normal ROIs. The abnormal ROIs were characterized by intensity,
abnormality, and detected ratio.
Key
words- canny,
ultrasound, MIC, pre-process, pixel
I INTRODUCTION
The
cervical cancer can be viewed by the ultrasound scan (or) MRI scans. The
ultrasound scanned image is taken for the entire process. The ultrasound scan
is more comfortable than MRI scan for diagnosis. It is not affect
the human body because it does not use a radiation. Ultrasound doesn’t emit
radiation. There are different types of algorithms were developed for uterine
cancer detection. An ultrasound device uses sound waves that can’t be heard by
humans. The sound waves make a pattern of echoes as the bounce off organs
inside the pelvis. Echoes’ create a picture of uterus. Uterine cancer is also
known as endometrial cancer. The two main types of endometrial cancer are:
[1] Endometroid adenocarcinoma
[2]
Uterine carcinosarcoma
Endometroid Adenocarcinoma: This type of uterine cancer forms in the
glandular cells of uterine lining, it accounts for as much as 75 present of all uterine cancers. Endometroid adenocarcinoma
commonly detected early and as a high cure rate.
Uterine Carcinosarcoma: This
rate form uterine cancer felt to be an endometrial cancer. It has elements of
both adenocarcinoma and sarcoma. These cancer have a
high risk of spread to lymph nodes and other parts of the body.
Ultrasound or ultra
sonography is a medical imaging technique. Ultrasound is used in
medicine to view internal organs of the body. It can also use to locate
objects. Ultrasound scans are used to detect problems in the liver, heart and
kidney (or) uterine. That uses high frequency sound waves and their echoes. The
sound waves travel in to our body and a boundary between tissues. The most
noticeable advantages of ultrasound scanning are safety, cost effectiveness,
speed, easy handling and portability. Ultrasound is based on the principle of
sound wave echoes. Sound wave travels from the probe to the object, passes
through it and is continuously reflected back to the probe from multiple points
inside the object. Ultrasound involves sound wave of frequency in the range of
megahertz; typically this ranges between 3.5-10 MHz
the machine display the two dimensional image. The quality of ultrasound images
is limited by granular speckle noise. This makes it difficult to segment the
images. The image is pre-processed in order to crop it such that unnecessary
portions as well as the speckle noise are removed. We use a morphological
cleaning algorithm to clean the image. Then it is segmented by an algorithm
which uses a collection of rules to locate the cancer and morphological
concepts to segment the image.
II RELATED RESEARCH WORK
MRI
stands for Magnetic Resonance Imaging. The scan uses radio waves and very
strong magnets to produce images of soft tissues. No x-rays are used. Magnetic resonance imaging (MRI) devices can
scan the inside of the body in detail, to spot even the earliest signs of
cancer or other abnormalities [3, 7]. It uses a magnetic field and radio waves
to take pictures inside the body. It is especially helpful to collect pictures
of soft tissue such as organs and muscles that don‘t
show up on x-ray examinations [2, 6]. MRI is accurate in diagnosing a fibroid
with a sensitivity of 88%–93% and a specificity of 66%– 91% [17]. One way to
think of an MRI scan is a water x-ray (although no actual x-rays are involved).
Normal x-rays image calcium, so they are good to see bones.MRI
scans image water, which makes them very useful because all tissues of the body
contain various amounts of water. This allows high resolution pictures of many
organs and tissues to be taken that are invisible to standard x-rays. Magnetic
Resonance Imaging (MRI) is an advanced medical imaging technique used to
produce high resolution images of the parts contained in the human body. MRI
imaging is often used when treating brain tumors.
These high resolution images are used to examine human
brain development and discover abnormalities. Different images either
infectious or non-harmful are acquired from (MRI). The images that are acquired
are completely unprocessed. The images can be in the form of JPG, PNG formats etc.
Uterine
Fibroid Investigation System, the following [4, 5] are the steps implemented: Image
Pre-processing: Pre-processing technique consists of two steps, namely cropping
the image and removing the noise. Several filters are used for noise removal
that is well established in gray value image
processing.
Segmentation: Segmentation is the next
step applied on the pre-processed image. Image segmentation is an important
process to extract information from complex medical images. The segmentation
component is expressed in terms of production rules, which capture the
perceptual knowledge relevant to the domain. These rules will detect
appropriate boundaries.
Feature Extraction: The goal of
feature extraction is to obtain representative features that can be used to
determine the mode of treatment. The
shape-based features, i.e. diameter, area and compactness, are the essential
measures.
Diameter: It is measured and specified
by the radiologist as horizontal and vertical diameters in centimetres. After
segmenting the fibroid, the horizontal and vertical diameters are calculated in
pixels and converted to centimetres.
Area: The area of the fibroid is the
number of pixels inside the fibroid. It is used to specify the size of the
fibroid. It can also be found by the formula A= pi*a*b/2
Compactness:
The compactness of a region is defined as the ratio of the square of the
perimeter of a region to its area, i.e. compactness = perimeter2/area, where
the perimeter is the distance around the boundary of the fibroid and the area
is the number of pixels inside the fibroid.
Magnetic
Resonance Imaging (MRI) is an advanced medical imaging technique used to
produce high resolution images of the parts contained in the human body. MRI
imaging is often used when treating brain tumors.
These high resolution images are used to examine human
brain development and discover abnormalities. MRI scan is done in an enclosed
space, so the people who are claustrophobic,
i.e. fearful of being in a closely enclosed surface, are facing problems with
MRI to be done. RI scans involve really loud noises wile processing because
they involve a really big amount of electric current supply MRI scanners are
usually expensive.
III. PROJECT DESCRIPTION
Ultrasound
scan makes use of sound waves to generate images of the internal organs of the
body. A gel will be applied on the abdomen to give a good contact for the
probe. The radiologist who performs the scan will move the probe over the
abdomen and the image will be displayed on the screen. The scan is completely
painless. The scan usually takes 10 to 15 minutes and you may be asked to wear
a gown. The ultrasound scanner looks a bit like a home computer system. There
is a hard-drive, keyboard and a display screen, and a hand-held sensor. The
sensor sends out sound waves and picks up the returning echoes. Pictures of the
inside of your body are displayed on the screen. These pictures are constantly
updated, so the scan can show movement. The sound waves travel at different
speeds depending on the type of tissue. An ultrasound gel is placed on the
transducer and the skin to allow for smooth movement of the transducer over the
skin and to eliminate air between the skin and the transducer for the best
sound conduction.
Ultrasound
images muscle and soft tissue very well and is particularly useful for
delineating the interfaces between solid and fluid-filled spaces. It renders
"live" images, where the operator can dynamically select the most
useful section for diagnosing and documenting changes, often enabling rapid
diagnosis. It has no known long-term side effects and rarely causes any
discomfort to the patient, and is relatively inexpensive compared to other
imaging modalities. A fundamental principle of ultrasound imaging is that there
is trade-off between penetration and
resolution: The lower 0frequencies (3.5 MHz for abdominal scanning), the better
the penetration (up to 15 cm), but the poorer the resolution (several mm.)
Conversely, the higher the frequency
(10 MHz for carotid artery imaging) the less the penetration (only a few cm)
but the better the resolution (less than an mm). Here proposed ultrasound
imaging technique to detect
cancer. Uterine cancer image captured from the
ultrasound scan.
Pre-processing:
Image
pre-processing, also called image restoration, and involves the correction of
distortion, degradation, and noise introduced during the imaging process. This
process produces a corrected image that is as close as possible, both
geometrically and radiometrically, to the radiant energy characteristics of the
original scene. Radiometric and geometric are the most common types of errors
encountered in remotely sensed image. Image pre-processing use the redundancy
in images. Image pre-processing some filters are using to remove the noise. Pre-Processing technique consists of
two steps, namely cropping the image and removing the noise.
Fig.1 Uterine cancer investigation system
Image segmentation: Segmentation is
the next step applied on the pre-processed image. Image segmentation is an
important process to extract information from complex medical image. The canny
edge detector first smoothens the image to eliminate noise.Then it finds the image gradient to highlight
regions with high spatial derivatives. After that it perform tracking along
these regions and suppresses any pixel that is not at the maximum. The gradient
array at this moment can further be reduced by hysteresis which is used to
track along the remaining pixels that have not been suppressed. Hysteresis uses
two thresholds and if the magnitude is below the first threshold, it is set to
zero. Canny Edge Detection Technique: The following shows the canny edge
detection algorithm steps. The algorithm runs in 5 separate steps.
1.
Smoothing: Blurring of the image to remove noise.
2.
Finding gradients: The edges should be marked where the gradients of the image
have large magnitudes. The gradient magnitudes (also known as the edge
strengths) can then be determined as a Euclidean distance measure by applying
the law of Pythagoras.
3.
Non-maximum suppression: Only local maxima should be marked as edges. Double
thresholding: Potential edges are determined by thresholding.
4.
Edge tracking by hysteresis: Final edges are determined by suppressing all
edges that are not connected to a very certain (strong) edge.
Feature
Extraction: The goal of feature extraction is to obtain representative features
that can be used to determine the mode of treatment. The shape-based features, i.e. abnormality,
intensity and detected ratio are the essential measures.
Classification:
Uterine cancer stages classified in to 3 types they are 1. Normal, 2.
Pre-cancer, 3. Cancer
Normal:
Uterine cancer have cancer that has not spread outside the uterus. This cancer confined to the inner
layer of cells of the uterus (endometrium).
Pre-cancer: uterine cancer that invades less than one
half of the muscle wall of the uterus.
Cancer: uterine
cancer that invades more than one half of the muscle wall of the uterus.
IV
EXPERIMENTAL RESULTS
Uterine
cancer image captured from the ultrasound scan. Read the original images from
ultrasound system. Morphological image cleaning (MIC) algorithm using these
structuring elements of operations such as opening-closing, closing-opening is
done to remove speckle noise.
The
edges should be marked where the gradients of the image have large magnitudes.
The gradient magnitudes (also known as the edge strengths) only local maxima
should be marked as edges. Double thresholding Potential edges are determined
by thresholding. Edge tracking by hysteresis: Final edges are determined by
suppressing all edges thatare not connected to a very
certain (strong) edge. The edge-pixels remaining after the non-maximum
suppression step are (still) marked with their strength pixel by-pixel. Many of
these will probably be true edges in the image, but some maybe caused by noise
or colour variations for instance due to rough surfaces. The simplest way to
discern between these would be to use a threshold, so that only edges stronger
that a certain value would be preserved. The Canny edge detection algorithm
uses double thresholding.
Fig .2 Input image
Fig. 3 MIC image
Fig. 4 canny edge image
V
CONCLUSION
The ultrasound methods are used in
medical image processing. It can be
used to give more information about cancer detection, segmentation and
classification. The target area is segmented and the evaluation of this tool
from the doctor and this helps the doctors in diagnosis, the treatment plan
making and state of the cancer monitoring. In future, the system can be
improved by adapting more segmentation algorithm to suit the different medical
image segmentation. Using colour based image segmentation.
It is possible to reduce the computational cost avoiding feature calculation
for every pixel in the image.
VI FUTURE WORKS
In future, we can classify ultrasound
uterine cancer in to three stages such as normal, pre-cancer and cancer. Normal
stage uterine cancer have cancer that as not spread
outside the uterus. This cancer confined to the inner layer of cell of the
uterus (endometrium). Pre-cancer stage uterine cancer that invades less than
one half of the muscle wall of the uterus. Cancer stage uterine cancer that
invades more than one half of the muscle wall of the uterus. These three stages
will be mentioned as histogram equalize graph.
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